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BioSolveIT GmbH docking software seesar
Docking Software Seesar, supplied by BioSolveIT GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/seesar+docking+software/seesar+software/pmc12260087-71-24-29
Average 90 stars, based on 1 article reviews
docking software seesar - by Bioz Stars, 2026-09
90/100 stars

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Article Title: Design, synthesis, biological evaluation and molecular modelling studies of oxoacetamide warhead containing indole-quinazolinone based novel hybrid analogues as potential pancreatic lipase inhibitors
Article Snippet: A novel series of indolyl oxoacetamide-quinazolinone hybrid analogues (9aa–9df) were designed, synthesized, and evaluated for their in vitro pancreatic lipase (PL) inhibitory potential which may lead to efficient anti-obesity agents.. All the synthesized hybrid analogues exhibited moderate to potent PL inhibitory activity (IC50 = 32.51 to 4.86 mM).. Among all the analogues, 9ak, 9af, 9aj, and 9ah were found to have the most potent PL inhibitory activity (IC50 = 4.86, 5.73, 5.83, and 5.94 mM respectively), as compared to orlistat (IC50 = 0.86 mM).

Article Title: Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells
Article Snippet: .. The refined three-dimensional model of the human A2a receptor (pdb code: 5K2B) was obtained from the GPCRdb ( https://www.gpcrdb.org ) and loaded into SeeSAR docking software (SeeSAR version 10.1; BioSolveIT GmbH, Sankt Augustin, Germany, 2020, www.biosolveit.de/SeeSAR ). .. Prior to docking, the binding site was established using the bound ligand ZM241385 and waters were excluded.

Article Title: Molecular modelling, synthesis and in vitro evaluation of quinazolinone hybrid analogues as potential pancreatic lipase inhibitors.
Article Snippet: Obesity is a multifactorial metabolic disorder, growing in an alarming rate across the world.. Amongst the numerous targets explored for obesity management, inhibition of pancreatic lipase (PL) is considered as one of the promising approaches.. Orlistat is the only PL inhibitory drug approved for long term treatment of obesity.



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